Pyrogen detection
Reliable and sustainable safety testing with monocyte activation tests (MAT).
Ensure safety of your drug candidate
The monocyte activation test (MAT) assay is an in vitro test widely used to detect pyrogens in a quick, efficient, and reliable manner. Compared to the traditional in vivo rabbit pyrogen test, the MAT assay is considered to be more sensitive and specific, providing better results in less time. By outsourcing your MAT assay to us, you can take advantage of our expertise in this field, ensuring that your results are accurate and your testing process is streamlined. With Mabtech, you can feel confident in the quality of your results and the speed of your testing process.
We offer the following types of MAT assays:
- IL-6 ELISA
- IL-1β ELISA
- IL-6/IL-1β FluoroSpot
The assays are performed with pooled human PBMCs and include endotoxin or non-endotoxin pyrogens as positive controls in accordance with Eu. Pharm Chapter 2.6.30 method A, B or C.
Our awards and ISO certification
Cofidence in every result
Our pyrogen detection services are built on scientifically validated MAT assays, run by experienced immunologists and supported by robust quality processes. From sample receipt to final report, we focus on speed, transparency, and reproducibility – so you can trust the data behind every release decision. Clear communication, detailed documentation, and a service-oriented mindset ensure your project moves forward with confidence.
Cheryl and David will help your project succeed.
Talk to our experts