ApoE is involved in the inflammatory responses during allergy-induced asthma.

ApoE involved in inflammatory responses

<a href="https://pubmed.ncbi.nlm.nih.gov/30872118/">Gordon et al. (J Allergy Clin Immunol, 2019)</a> at the NIH recently showed that apoE works as an endogenous, concentration-dependent pulmonary danger signal that primes and activates the NLPR3 inflammasome in BALF macrophages from asthmatic subjects to secrete IL-1β.

It is thus important to measure apoE in the context of inflammatory responses, and yes you guessed it, Gordon et al. used Mabtech ELISA Pro:&nbsp;<a href="/products/3712-1hp-2">human apoE </a>and <a href="/products/3752-1HP-2">mouse apoE</a>&nbsp;for that purpose.&nbsp;

Reference

<ul>
	<li><a href="https://pubmed.ncbi.nlm.nih.gov/30872118/">Gordon et al.,&nbsp;Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects.&nbsp;J Allergy Clin Immunol.&nbsp;2019</a> 
	.</li>
</ul>

Mabtech product used

<ul>
	<li><a href="/products/3712-1hp-2">ELISA Pro: Human apoE</a></li>
	<li><a href="/products/3752-1HP-2">ELISA Pro: Mouse apoE</a></li>
</ul>

ApoE involved in inflammatory responses

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