Intended use
This peptide pool is intended for studying immune responses against CMV in immunoassays such as ELISpot, FluoroSpot, and flow cytometry. It induces cytokine secretion from antigen-specific human CD4 and CD8 T cells. For research use only. Not for use in diagnostic procedures.
Description
The CMV peptide pool induces secretion of e.g., IFN-γ, IL-2, IL-5, and IL-13 from human CD4 and CD8 T cells. It contains 42 peptides from cytomegalovirus. The antigens represented in the peptide pool are pp50, pp65, IE1, IE2, and envelope glycoprotein B. 28 of the peptides are MHC class I-restricted and 14 are MHC class II-restricted. The synthetic peptides are >95% pure.
HLA types covered by the CMV pool:
HLA class I: HLA-A1, HLA-A2, HLA-A3, HLA-A11, HLA-A23, HLA-A24, HLA-A26, HLA-A30, HLA-B7, HLA-B8, HLA-B18, HLA-B27, HLA-B35, HLA-B40/60, HLA-B41, HLA-B44, HLA-B57/58, HLA-C7. HLA class II: HLA-DRB1*01, 03, 04, 05, 07, 08, 11, 15, 20, 24, 53, HLA-DPw2, HLA-DQB, HLA-DP3*14, 20